Program
Welcome and Introductions (3:00 - 3:20 pm)
Otto Miller room 109
Oral Presentations (3:30 - 5:05 pm)
Ecology & Genetics: OMH 109
| 3:30 pm - 3:50 pm | Determining the genetic control of neural tube malformation through genetic interactions with Idgf3 Presented by: Elli Fox and Kari Thorsen Advised by: Dr. Michelle Casad, Dept. of Biology [abstract]We are particularly interested in the gene that causes neural tube malformation. Based on epithelial tube morphogenesis similarities, we can use Drosophila melanogaster as a model for vertebrate neural tube formation. This genetic research will allow us to find the enhancer gene to further characterize the Idgf pathway. This is particularly important based on the effect of Idgf3 overexpression and its results on dorsal appendage malformation. |
| 3:55 pm - 4:15 pm | Survivorship of Columbian black-tailed deer (Odocoileus hemionus columbianus) on Blakely Island, Washington Presented by: John Hemenway and Urim Kim Advised by: Dr. Eric Long, Dept. of Biology [abstract]We estimated annual survivorship for a high-density population of Columbian black-tail deer (Odocoileus hemionus columbianus) located on Blakely Island, WA by using opportunistically collected, non-hunter killed skulls and extracting the first lower molar and determined the age at death by counting cementum annuli. We wanted to know how long deer live without predators and if survivorship differed between males and females. |
| 4:20 pm - 4:40 pm | Survivorship of male harvested Columbian black-tailed deer (Odocoileus hemionus columbianus) on Blakely Island, WA Presented by: Carly Kano and Itzia San Ramon Advised by: Dr. Eric Long, Dept. of Biology [abstract]Survivorship assesses the likelihood that an individual will make it to the subsequent year. In predator free environments survivorship can be influenced by resource availability, stochastic environmental components and the harvesting. Harvesting is typically non-random, deviates from patterns of natural mortality, and selects individuals of certain sex, age, and phenotypic class. Our study investigates hunter preference and looks to see if hunting patterns mimic natural mortality. * Best Oral Presentation awardee |
| 4:45 pm - 5:05 pm | Assessing genetic diversity in an island deer population Presented by: Shun-Je Bhark and Callista Nackviseth Advised by: Dr. Jenny Tenlen and Dr. Eric Long, Dept. of Biology [abstract]Island populations are vulnerable to reduced fitness due to small population sizes. This study analyzes two indirect markers of fitness, male survivorship and mitochondrial genetic diversity in Black-tailed deer (Odocoileus hemionus columbianus) by extracting DNA from bone. Sex-specific and mitochondrial primers were used to amplify sequences of interest, then PCR products were analyzed using gel electrophoresis. We will present preliminary data for sex identification of deer, and discuss challenges to and optimization strategies for amplifying products from bone DNA. |
Molecular Biology: OMH 118
| 3:30 pm - 3:50 pm | Constructing bioengineered proC2 mutants through in vivo E. coli cloning Presented by: Laarni Aguila, Leslie Rodriguez-Salas, Anh Tran and Joseph Pham Advised by: Dr. Derek Wood, Dept. of Biology [abstract]Constructing bioengineered Agrobacterium tumefaciens C58 proC2 mutants through in vivo E. coli cloning to observe variations in proline biosynthesis. We are observing the efficiency of our homology arms compared to CRISPR/Cas9 in creating mutants. Mutants can later be used to test different environmental stressors. Differences in proline production can help us better understand the relationship between ProC1 and ProC2 genes and answer the big question of why multiple proC genes are found in wild-type agrobacterium. |
| 3:55 pm - 4:15 pm | Optimization of CRISPR/cas9 System in Agrobacterium tumefaciens Targeting proC2 Presented by: Allie Kehret, Jordan Lewis, Hallee Decker and Erica Naibert Advised by: Dr. Derek Wood, Dept. of Biology [abstract]Our research has focused on adapting the CRISPR/cas9 system to create a proC2 mutant strain of Agrobacterium tumefaciens C58. We aim to find the optimal length of homology to the organism's genome in comparison to an inserted fragment of DNA to drive homology directed repair. Through this we are able to create a proC2 gene knockout to be used in further studies of gene duplication. * Best Oral Presentation awardee |
| 4:20 pm - 4:40 pm | Quantification of cellular free proline using the colorimetric ninhydrin assay and the Standard Addition Method Presented by: Loriel Arcangel, Alexandria Naftchi and Jonathan Mahlum Advised by: Dr. Derek Wood, Dept. of Biology [abstract]Using the Standard Addition Method, a simple analytical chemistry technique, our research shows that the classical colorimetric ninhydrin assay (commonly used for determining amino acid concentrations within cells) can be used to determine intracellular proline in a dependable range to do a qualitative and quantitative comparison of two different ProC genes within a complex cellular background. |
| 4:45 pm - 5:05 pm | Development of Agrobacterium tumefaciens C58 mutants via the CRISPR/Cas9 system to test proC1 (ATU-2209) function Presented by: Jodi Grantham, Cienn Joyeux, Nick Lee and Jeanna Ramirez Advised by: Dr. Derek Wood, Dept. of Biology [abstract]Without the production of proline from its surrounding environment, A. tumefaciens has two processes allowing for the biosynthetic creation of proline. Our research looks at the duplicity of these processes by creating a bacterial mutant using CRISPR as genetic editing tool. We hope to successfully create a mutant that has knocked out one of the two proC genes within A. tumefaciens to be able to further investigate why this species has retained two replicate genes. |
Biology & Chemistry: OMH 119
| 3:30 pm - 3:50 pm | Strain Diversification and Nodulation Success in Bradyrhizobium japonicum in the Face of Drought Presented by: Brian Pfau Advised by: Dr. Kimberly La Pierre, Smithsonian Institution [abstract]Soybean fields are often inoculated with the symbiotic bacterium Bradyrhizobium japonicum, which lives in root nodules in the plant and provides usable nitrogen in exchange for a carbon source. We sought to determine whether diversifying these inoculants with other USDA strains would make the inoculant population more successful in the face of drought. By most metrics, strain diversification did not increase nodule production compared to monocultures, but further study is needed to determine whether diverse inoculants can be designed to be more drought resistant than monocultures alone. |
| 3:55 pm - 4:15 pm | Comparison of algal biomass and organic content in Thatcher Bay pre and post restoration effort Presented by: Isabella Tsark Advised by: Dr. Tim Nelson, Dept. of Biology [abstract]Thatcher Bay, Blakely Island, WA was impacted by wood-waste. This resulted in elevated total organic composition, impacting the benthic habitat quality. Restoration efforts removed the wood waste and may have affected the organic content and algal biomass. In order to estimate the success of these conservation efforts we measured the current elemental concentrations of organic material and algal biomass in Thatcher and, as a control, Armitage Bay. These values are compared to pre-restoration conditions. |
| 4:20 pm - 4:40 pm | Synthesis and Characterization of a Homogeneous Cobalt Catalyst for the Hydrogenation of Acetone to Isopropanol Presented by: Joselyn Molina Advised by: Dr. Samantha Robinson, University of Washington [abstract]Homogeneous cobalt catalysts may provide viable alternatives for sustainable production of fuels, straying from the need of environmentally costly metals. This study explains the synthesis of the interested cobalt catalyst and its ability to be a more economically favorable means for the production of high value chemicals from a lower value feedstock. |
| 4:45 pm - 5:05 pm | Effects of Olfaction on Social Behaviors and their Neural Correlates in Peromyscus californicus Presented by: Erinn Campbell, Ngan Dang and Christine Spatacean Advised by: Dr. Janet Bester-Meredith, Dept. of Biology [abstract]To determine the effect of olfaction on social behavior, male and female Peromyscus californicus were intranasally injected with zinc gluconate to impede their sense of smell. These mice, as well as a control group, were subjected to numerous tests evaluating aggression, parental care, and ability to detect food. We also examined the neural correlates of these social behaviors by measuring the degree of arginine vasopressin expression in various brain regions. * Best Oral Presentation awardee |
Physiology & Sociology: OMH 128
| 3:30 pm - 3:50 pm | Baby steps: Child carrying strategies of urban individuals Presented by: Madison Hubble and Erika Bunge Advised by: Dr. Cara Wall-Scheffler, Dept. of Biology [abstract]The ability to conserve energy is an important aspect of a species' evolutionary survival. Carrying loads causes an increase in caloric cost per distance travelled, and carrying children can pose a large reproductive cost. In this project, we sought to determine if individuals in an urban context choose to carry or transport their children in energetically efficient ways. We also sought to determine the social factors which cause individuals to deviate from efficient carrying strategies. * Best Oral Presentation awardee |
| 3:55 pm - 4:15 pm | Mission Driven? Ethics and Capabilities at the Meso Organizational level in response to Homelessness Presented by: Madeline McDonald Advised by: Dr. Karen Snedker, Dept. of Sociology [abstract]This is a case study evaluation of one organization in Seattle Washington. Focusing at the meso level work on homelessness. Specifically, concerning fighting family homelessness. It engages the mission of the organization and draws upon direct interviews with employees. Then, applies a philosophical ethical theory to evaluate how ethics interacts with this engagement. This paper questions why an ethical approach may be necessary to a resolution, as we continue to see growing numbers of homelessness. |
| 4:20 pm - 4:40 pm | Factors that Drive opinions on Abortion, Suicide, and Capital Punishment Presented by: Johnny Harvill Advised by: Dr. Joshua Tom, Dept. of Sociology [abstract]I looked at abortion, suicide, and capital punishment data against the lens of religion to see how religion offers positive or negative attitudes. I then control for multiple other variables to see how religion holds up or if it washed out due to other factors. |
Engineering & Physics: OMH 225
| 3:30 pm - 3:50 pm | Pill Bot Presented by: Robo-Medics (Lorena Ferreira, Leanna Temple, Joanna Dickinson, Nick Sharp and Erin Okuna) Advised by: Dr. Adam Arabian, Dept. of Engineering [abstract]An autonomous robot that is placed within medical facilities and navigates to specific rooms at designated times to deliver medication to nurses/patients. |
| 3:55 pm - 4:15 pm | VAST Automated Storage Presented by: Tyler Wadekamper, Jonathan Ho, John Kim, Joshua Mason and Luke Swatosh Advised by: Dr. Adam Arabian, Dept. of Engineering [abstract]VAST is a tall storage shelf that automatically stores heavy items for people who use a wheelchair. The unit stores items at a height of up to 7 feet, then retrieves them at the press of a button. |
| 4:20 pm - 4:40 pm | Remote Item Manipulator Presented by: Alex Tran, David Meyer, Kieran Jackson, Grant Kalfus and Linnea Weicht Advised by: Dr. Adam Arabian, Dept. of Engineering [abstract]The Remote Item Manipulator (RIM) is a remotely controlled arm designed to work in the presence of corrosive chemicals, like hydrofluoric acid. The operator of this arm will send commands to the RIM to manipulate objects within the hazardous environment while remaining out of harm themselves. * Best Oral Presentation awardee |
| 4:45 pm - 5:05 pm | Martin Square Mystery Presented by: Mikayla Valentin and Hannah Roosendaal Advised by: Dr. Lane Seeley, Dept. of Physics [abstract]We are investigating the acoustical phenomenon of the famous Martin Square "squeak." This is a part of our Experimental Methods III project, and it's gained enough interest among students and faculty that we feel we should share the mystery with everyone. |
Mathematics (Session 1): OMH 244
| 3:30 pm - 3:45 pm | Agree with me, K? Interrater Reliability Using Cohen's Kappa Presented by: Jessica Fossum Advised by: Dr. Brian Gill, Dept. of Mathematics [abstract]This project explores interrater reliability, which is the level of agreement between two coders. Specifically, we look at the mathematics behind Cohen's Kappa and its extensions, which are ways of measuring the agreement. Functions to calculate the statistic are coded in R, and an example application is given from psychological research. |
| 3:50 pm - 4:05 pm | Face Recognition and PCA Presented by: Sion Park Advised by: Dr. Wai Lau, Dept. of Mathematics [abstract]This project explores the concept behind Principal Component Analysis(PCA) and how it is used in Face Recognition process. |
| 4:10 pm - 4:25 pm | Preprocessing with Clustering to Avoid Convolution Presented by: Robert Chung Advised by: Dr. Wai Lau, Dept. of Mathematics [abstract]Convolutional Neural-Networks (CNN) are used extensively for machine learning. However, CNNs are expensive; we investigate an approach of preprocessing images such that we can avoid convolution. We use this approach to classify handwritten digits, still using a Neural-Network architecture. * Best Oral Presentation awardee |
| 4:30 pm - 4:45 pm | Oh Deer! Comparison of Clustering Algorithms on Deer Data Presented by: Destiny Cleary Advised by: Dr. John Hossler, Dept. of Mathematics [abstract]This presentation focuses on clustering, a machine learning technique. Two types of clustering are compared: k-means and hierarchical; then they are applied to a dataset for black-tailed deer to find patterns in the data. * Best Oral Presentation awardee |
| 4:50 pm - 5:05 pm | Lost in the Shuffle: Analyzing Random Chance in a Deck of Cards Presented by: Mary Kate La Bar Advised by: Dr. John Hossler, Dept. of Mathematics [abstract]Have you ever wondered how many times you need to shuffle a deck of cards until it is random enough? Have you ever been dealt a hand of cards and wondered if the deck was even shuffled at all? As we explore the mathematics behind the simple act of shuffling cards, we learn our techniques may not be as random as we thought. |
Mathematics (Session 2): OMH 245
| 3:30 pm - 3:45 pm | Taxicab Geometry Presented by: Sophie Hummer Advised by: Dr. Robbin O'Leary, Dept. of Mathematics [abstract]Comparing ellipses, hyperbolas, circumscribed and inscribed circles with taxicab and Euclidean geometries |
| 3:50 pm - 4:05 pm | Accept or Reject Clients' Loan Applications Presented by: Jezen Alexander Advised by: Dr. Brian Gill, Dept. of Mathematics [abstract]The objective of this project is to predict the likelihood that clients would have difficulties in paying off their loans, by creating a model using logistic regression. We will also look at how the dollar amount loss that loan providers experienced would affect their decisions through simulations. The data used is from Home Credit Group. |
| 4:10 pm - 4:25 pm | The Mandelbrot Set Presented by: Kole Yoshimura Advised by: Dr. Brian Gill, Dept. of Mathematics [abstract]The Mandelbrot Set is considered one of the most beautiful objects in Mathematics. We will be looking at the Mandelbrot Set, its generalizations, and its relationship with Julia Sets. |
| 4:30 pm - 4:45 pm | The Chinese Remainder Theorem Through Inquiry Presented by: Rebecca Butler Advised by: Dr. Robbin O'Leary, Dept. of Mathematics [abstract]Number theory is classically taught through the rote presentation of theorems and proofs supported by subsequent problem sets which employ or build upon these theorems. Inquiry based texts seek to shift this paradigm by centering instruction about student discovery of course material rather than relying upon blunt explanation alone. This project develops an inquiry based tutorial regarding the Chinese Remainder theorem in the pedagogical style of the University of Washington Tutorials in Introductory Physics. |
| 4:50 pm - 5:05 pm | Knot Theory and the 2-Variable Kauffman Polynomial Presented by: Leslie Mavrakis Advised by: Dr. John Hossler, Dept. of Mathematics [abstract]In knot theory, we often ask if two knots or links are different. That is, if I have two tangled up strings can I determine they are different knots? Here, invariants are properties of knots which remain unchanged regardless of what diagram of a knot is used. In this presentation, we explore a specific polynomial invariant: the 2-Variable Kauffman Polynomial and the impact on the polynomial when changes in orientation are made. * Best Oral Presentation awardee |
Mathematics (Session 3): OMH 246
| 3:30 pm - 3:45 pm | Baseball Statistics Presented by: Sarah Farrell Advised by: Dr. John Hossler, Dept. of Mathematics [abstract]This project is looking at the statistics of the winning team in a fictional baseball league. Specifically, the number of games we would expect the winning team to win. |
| 3:50 pm - 4:05 pm | Explorations of Non-transitive Relationships Between Dice Presented by: Alexander Ticknor Advised by: Dr. Steve Johnson, Dept. of Mathematics [abstract]My project is the relationships between different sets of dice with sides not the same as a regular die. I looked especially at what happens when more than one of each die is rolled at the same time as another die. |
| 4:10 pm - 4:25 pm | The Problem with Proof Presented by: Patrick Lee Advised by: Dr. Jerilynn Lepak, Dept. of Mathematics [abstract]Students all across the U.S. struggle with proof based learning in classes such as Abstract Algebra, Number Theory, and Geometry. To find the source of this struggle I have analyzed a common core-based geometry textbook for high school students to decipher whether students are being offered enough opportunities to learn proof and logic that can be built upon in following mathematics classes. |
| 4:30 pm - 4:45 pm | Analysis and Synthesis of Direct Instruction and Inquiry-Based Learning Curricula Presented by: Brianna Warner Advised by: Dr. Jerilynn Lepak, Dept. of Mathematics [abstract]My project explores direct instruction and inquiry-based learning as two different teaching strategies in mathematics education. The purpose of my project is to conduct an analysis of direct instruction and inquiry-based learning curricula in order to synthesize these contrasting approaches to teaching in a five-day lesson plan that differentiates mathematics instruction. * Best Oral Presentation awardee |
| 4:50 pm - 5:05 pm | Markov Chains and their Applications in Baseball Presented by: Mark Brumberg Advised by: Dr. John Hossler, Dept. of Mathematics [abstract]This project explores the relationships between statistics and baseball. Specifically, it uses Markov chains to model the progression of a baseball game. First, it explores the Markov chain and how they work using examples unrelated to baseball, then applies those concepts to baseball. |
Poster Presentations (5:15 - 6:30 pm)
Otto Miller Lobby and 2nd Floor
Biochemistry
Presented by: Caroline Kim. Identifying the effect of S2 and S3 isoforms on RecA function of Mycroplasma Genitalium. Advised by: Dr. Gwendolyn Wood, University of Washington and Dr. Ben McFarland, Dept. of Chemistry & Biochemistry. [abstract]This research will be looking into a sexually transmitted pathogen, Mycoplasma genitalium (MG). With RecA, MG goes through homologous recombination, causing MG to be resistant to antibodies. Furthermore, it was found that MG expresses three isoforms of RecA, which are L1, S2, and S3. The aim of this research is to study the purpose of S2 and S3 isoforms and what their effects are on L1 activity as well as the RecA.
Biology
Presented by: Laarni Kendra Aguila. Characterization of small heat shock proteins in the tardigrade, Hypsibius exemplaris. Advised by: Dr. Jenny Tenlen, Dept. of Biology. [abstract]Small heat shock proteins (sHSP) are known to provide heat tolerance in organisms such as Drosophila melanogaster by binding to misfolded proteins to prevent deleterious interactions. It’s speculated that this is an evolutionary adaptation to provide a layer of protection during crucial developmental stages. To test this prediction, I am investigating the presence and expression of sHSP in a phylogenetically related organism, Hypsibius exemplaris. This study should provide insight to the developmental role of sHSP.
Presented by: Cameron Ashton. Endurance and Aging: Measuring Gender Differences in Ultramarathoners. Advised by: Dr. Cara Wall-Scheffler, Dept. of Biology. [abstract]Recent scientific literature suggests that post-reproductive women are better suited for endurance activities than other age and gender groups. We are using published ultramarathon race results to investigate this claim, predicting that the performance of women will decline more slowly with age due to changes in thermoregulation.
Presented by: Haley Ballard and Hannah Thompson. Survivorship of Harvested Female Odocoileus hemionus columbianus. Advised by: Dr. Eric Long, Dept. of Biology. [abstract]We determined the age of female harvested Columbian black-tailed deer (Odocoileus hemionus columbianus) on Blakely Island using cementum annuli present on the lower first molar. Using the determined ages, we compared the age of death for harvested and non-harvested females to determine if hunters are selecting for older deer because of size selectivity. We also compared the sex ratio of harvest deer to determine if hunters were exhibiting sex selectivity.
Presented by: Victoria Beavers, Olivia Sagarang. Effects of Salinity on the Production of Stress Pheromone Anthopleurine in Anthopleura elegantissima. Advised by: Dr. Ryan Ferrer, Dept. of Biology. [abstract]The aggregating anemone (Anthopleura elegantissima) emits the alarm signal anthopleurine that triggers a predator avoidance behavior in neighboring clone anemones. Our previous experiments demonstrated that changes in salinity can affect the response to anthopleurine. Here we examine the effect of salinity on the production of anthopleurine. Our findings could provide insights on how chemical signaling could be impacted by shifting environmental conditions associated with climate change.
Presented by: Logan Butler Sam Simpson. Fluctuating Asymmetry in Colombia Black Tailed Deer. Advised by: Dr. Eric Long, Dept. of Biology. [abstract]We are researching the presence of fluctuating asymmetry in skull anatomy as well as dentition in Colombia black-tailed deer resident to Blakely Island as compared with mainland deer.
Presented by: Hayley Cheyney Kane. The use of bouts during activity decreases women's core temperature more than men's. Advised by Dr. Cara Wall-Scheffler, Dept. of Biology. [abstract]Recent studies have recognized the importance of water transport for the subsistence strategies of many human populations. We are interested in how thermoregulatory strategies during water transport might compare with over-ground transport. For example, when people practice “bout” walking—walking in short bursts interspersed with periods of rest—they reset hypothalamic regulation of pace and potentially are able to walk further. Here we test whether bout-locomotion might also aid people in minimizing the heat gain during canoeing. We monitored eight people (4 men; 4 women) independently paddling continuously across a lake (avg ambient temp=23.9°C; avg humidity=61.7%). We measured participants’ blood perfusion, heart rate (HR), core body temperature, and paddling speed during a trial, which consisted of periods of paddling (6 or 12 minutes) regularly interspersed with periods of rest (also 6 or 12 minutes). A single repeated-measures ANOVA was done for each dependent variable, with sex as a factor. People’s paddling speed and HR did not change whether they had a long rest (LRE) or short rest (SRE) prior to paddling (p=0.368; p=0.489), nor was there a significant sex effect on speed or HR (p=0.368; p=0.560); however, females’ core temperature decreased during long rows (LRO) when the LROs were preceded by a LRE, whereas their core temperature increased when the LRO was preceded by a SRE (p=0.064). This is potentially due to blood perfusion to the biceps during LROs being dependent upon the length of the preceding rest (p<0.001). Thus, bout-paddling might be a strategy for maintaining thermoregulation among women. * Best Poster awardee
Presented by: Madison Cooper and Kora Krumm. Species determination of Ulvoid algae through genotyping: What are the environmental implications?. Advised by: Dr. Tim Nelson, Dept. of Biology. [abstract]Ulvoid algae is especially difficult to identify via traditional methods, such as dichotomous keying. This project aims to streamline taxonomic classification of algal species through DNA sequence analysis. Local samples of Ulvoid were obtained, and two target genes were sequenced via PCR amplification. Ulvoids have a detrimental impact on marine ecosystems in the Pacific Northwest due their role in eutrophication, and reliable identification can help mitigate these effects.
Presented by: Grace Duffey. Identifying putative Piwi homologs in tardigrade species Hypsibius exemplaris. Advised by: Dr. Jenny Tenlen, Dept. of Biology. [abstract]Piwi proteins are a subfamily of the Argonaute family and function in germline maintenance. This makes Piwi highly conserved in animals, but it has not been identified in tardigrades. I plan to present phylogenetic trees identifying putative Piwi homologs in Hypsibius exemplaris as well as PCR results that confirm their presence in the tardigrade genome. I will also present predicted structures of putative Piwi homologs based on known Piwi crystal structures.
Presented by: Grace Duffey, Callista Nackviseth, Brian Pfau and Kari Thorsen. Developing an Assayable Mutant of Agrobacterium tumefaciens C58 to Assess Conjugal Transfe. Advised by: Dr. Derek Wood, Dept. of Biology. [abstract]The plant pathogen Agrobacterium tumefaciens may bear multiple copies of a gene for producing proline as a counter-defense mechanism against its host, allowing it to spread copies of its virulent Ti plasmid throughout the population to begin infection. Using molecular techniques, we developed a strain of A. tumefaciens C58 suitable to assess how this process, known as conjugal transfer, may change in frequency based on the number of copies of this proline gene present in the genome.
Presented by: Jodi Grantham and Tristen Wilson. Observing the effects of leaf loss on diurnal rhythmicity through branch orientation. Advised by: Dr. Cara Wall-Scheffler, Dept. of Biology. [abstract]Tree sleeping, defined as the drooping of branches at night, can be quantified over 24-hour periods. To better understand how leaf loss affects tree sleeping, we quantified tree branch movements of a sunset maple from the autumn equinox to the winter solstice.
Presented by: Menna Hailemariam. Identification and characterization of Hedgehog pathway proteins in the tardigrade species Hypsibius exemplaris. Advised by: Dr. Jenny Tenlen, Dept. of Biology. [abstract]The Hedgehog signaling pathway transmits information to embryonic cells required for proper cell differentiation. It is an evolutionarily conserved pathway that has critical roles in embryonic development. The pathway was originally discovered and studied in Drosophila melanogaster, but it is also present in Caenorhabditis elegans, and vertebrates, and its role in all three of these is similar. Since Drosophila melanogaster, Caenorhabditis elegans and Hypsibius exemplaris are all part of the Ecdyscozoans superphylum, tardigrades are being developed as a model organism to explain the evolution of the pathway. This project addresses two questions: is the hedgehog pathway present in Hypsibius exemplaris? How did it evolve in Ecdyscozoans? Based on what is known about the pathway in Drosophila melanogaster and Caenorhabditis elegans, a list of hedgehog related genes was created. The presence of these genes in the tardigrade genome was first verified using bioinformatic tools. These tools were then used to construct a phylogenetic tree proposing an evolutionary model for the pathway. These genes will then be amplified from tardigrade genomic and complementary DNA using a polymerase chain reaction, to confirm whether or not they are expressed. This study will be the first to provide evidence of the presence of a functional hedgehog pathway in tardigrades. Moreover, it will not only be valuable when trying to explain the evolution of hedgehog, but it may also provide a new perspective in understanding germline development.
Presented by: Nikki Harasta and Jeanna Ramirez. Localization and initial analysis of MAPK and IP3K-Akt signaling pathways in hemocytes of the pond snail, Lymnaea stagnalis. Advised by: Dr. Richard L. Ridgway, Dept. of Biology. [abstract]Recent evidence suggests immune cells (hemocytes) of mollusks utilize several signaling pathways in their active responses to bacterial infections or tissue damage. We have examined the role of two kinases involved in the motility changes associated with such responses: ERK 1/2, a key kinase in the MAPK cascade and Akt, a key kinase in the PI3K pathway. Our hypothesis is that these two pathways act in concert to enable activation of motile phagocytosis.
Presented by: Madison Hubble, Erika Bunge. Baby steps: Child carrying strategies of urban individuals. Advised by: Dr. Cara Wall-Scheffler, Dept. of Biology. [abstract]The ability to conserve energy is an important aspect of a species' evolutionary survival. Carrying loads causes an increase in caloric cost per distance travelled, and carrying children can pose a large reproductive cost. In this project, we sought to determine if individuals in an urban context choose to carry or transport their children in energetically efficient ways. We also sought to determine the social factors which cause individuals to deviate from efficient carrying strategies.
Presented by: Cienn Joyeux and Ngan Dang. Exploring the impact of how induced anosmia affects paternal recognition in new fathers in the species Peromyscus californicus.. Advised by: Dr. Janet Bester-Meredith, Dept. of Biology. [abstract]In monogamous and biparental species like the California mouse (Peromyscus californicus), fathers spend the same amount of time with offspring as mothers. Paternal care plays an important role in offspring development. In this study, I analyzed the effect of anosmia induced via intranasal injections of zinc gluconate on the male’s ability to discriminate his pups from foreign pups. Changes in paternal recognition were documented beginning shortly after birth until 31 days after weaning.
Presented by: Allie Kehret, Jordan Lewis, Hallee Decker and Erica Naibert. Optimization of CRISPR/Cas9 System in Agrobacterium tumefaciens Targeting proC2. Advised by: Dr. Derek Wood, Dept. of Biology. [abstract]Our research has focused on adapting the CRISPR/cas9 system to create a proC2 mutant strain of Agrobacterium tumefaciens C58. We aim to find the optimal length of homology to the organism's genome in comparison to an inserted fragment of DNA to drive homology directed repair. Through this we are able to create a proC2 gene knockout to be used in further studies of gene duplication.
Presented by: Kora Krumm. Superwomen: sexual dimorphism in energy expenditure during exercise. Advised by: Dr. Cara Wall-Scheffler, Dept. of Biology. [abstract]Men and women exhibit differing tendencies for energy management. People were monitored for energy expenditure during load-bearing exercise, and females demonstrated significantly fewer calories burned than did men. We see this result because energy-efficient load-carrying confers increased fitness in females, who traditionally traveled during pregnancy and child-carrying.
Presented by: Bryan Loew. Ultrastructure of vegetative cells in the marine alga Ulvaria obscura with reference to dopamine production. Advised by: Dr. Richard L. Ridgway, Dept. of Biology. [abstract]Ulvaria obscura is unique in producing dopamine in response to stressors or as a defense molecule against herbivores. We have examined the structure of vegetative cells within this alga through light and transmission electron microscopy methods to analyze specific subcellular components and their potential roles in dopamine production and release.
Presented by: Angelina Luthi. Exploration of Tudor gene conservation in the Hypsibius exemplaris (tardigrade) genome. Advised by: Dr. Jenny Tenlen, Dept. of Biology. [abstract]A gene called Tudor is involved in a wide variety of processes during development. There is evidence to suggest that Tudor exists in tardigrades. Tardigrades are microscopic organisms that can survive in extreme conditions. Eleven putative Tudor sequences were discovered within the genome of a tardigrade species (H. exemplaris). We will discuss efforts to verify expression of these genes in living tardigrades. The discovery of these proteins will be useful for future studies exploring Tudor function in development and could demonstrate how morphological diversity evolves in developmental mechanisms.
Presented by: Andrew Metz. Comparing Flight Patterns: How a Common Pesticide Impacts Moth Flight. Advised by: Dr. Ryan Ferrer, Dept. of Biology. [abstract]Common pesticides that are used can have unintended consequences by damaging non-target species. This project examines how carbaryl impacts the flight patterns of the tobacco hornworm moth (Manduca sexta) compared to two attractive floral odors.
Presented by: Alexandria Naftchi and Nicholas Lee. Correlating Reactive Oxygen Species Release and Regenerative Neuritic Outgrowth of an Identified Neuron in the Pond Snail, Lymnaea stagnalis. Advised by: Dr. Richard L. Ridgway, Dept. of Biology. [abstract]Model organisms such as Lymnaea stagnalis are often helpful in studying microscopic physiological phenomena such as neural regeneration. Here, we investigated the relationship between release of reactive oxygen species (ROS) by neurons and glial cells following crushing of a peripheral nerve trunk and regenerative outgrowth of the interneuron LPeD1. ROS emitted from crush sites, visualized using specific fluorescent probes, was positively correlated with neuronal sprouting of LPeD1 identified using iontophoretically labelled axons via live-cell imaging.
Presented by: Leslie Rodriguez-Salas. Isolation and characterization of vasa in Hybsibius exemplaris. Advised by: Dr. Jenny Tenlen, Dept. of Biology. [abstract]The vasa gene has been found to be conserved in a diverse range of Metazoans. Studies of vasa indicate it has an essential role in germline development. However, the exact mechanism and functions of vasa are unknown, possibly due to differences in expression in different species. Using tardigrades as a laboratory model, this research project aims to further our understanding in germline development and evolution.
Presented by: Enoch Tham. Effects of food concentration on Pogonomyrmex occidentalis ant foraging trails. Advised by: Dr. Ryan Ferrer, Dept. of Biology. [abstract]The Pogonomyrmex genus of ants are known to use chemical trails to recruit fellow worker ants in gathering from discovered food sources. However, current literature has not explored whether chemical trails leading to food sources of varying concentrations will influence the decisions of Pogonomyrmex ants. Our research seeks to determine whether chemical trail cues associated with varying food concentrations will influence decision making in Pogonomyrmex occidentalis ants. * Best Poster awardee
Chemistry
Presented by: Jacob Baillie and Joselyn Molina. Replacing Noble Transition Metal Catalysts with Green Alternatives. Advised by: Dr. Samantha Robinson, University of Washington. [abstract]Sustainable chemistry is increasingly relevant as the need to create viable alternatives for sustainable and less environmentally costly reactions has become evident. More abundant metals are seeing increasing usage in catalysts in energy industries such as converting natural gas into methanol and production of isopropanol from acetone. In this work, alternative catalysts using more environmentally sustainable metals are produced and tested. Further research is needed to confirm the efficacy of these complexes for their respective functions.
Presented by: Andrew Y. Lee. The Exploration of Sulfur Hydrogen Bonds. Advised by: Dr. Daniel Schofield, Dept. of Chemistry & Biochemistry. [abstract]Hydrogen bonds are interactions conventionally described as X-H ---- X, in which X is N, O, or F. In our research, we examine the more unconventional hydrogen bond interactions of sulfur using vapor-phase infrared (IR) spectroscopy. When a hydrogen bond donor (i.e. X-H) complexes to a hydrogen bond acceptor (X), an increase in bond length is observable in an IR spectrum through the emergence of a lower energy absorption band.
Presented by: Anton Taraskin. ab initio Calculations of Changes in Sulfur’s Orbital Energies and Sizes with Oxidation State as a Means of Explaining Hypervalency. Advised by: Dr. Kevin Bartlett, Dept. of Chemistry & Biochemistry. [abstract]An examination of how sulfur's 3s, 3p and 3d orbitals compare in size and energy to fluorine's 2p orbitals depending on the basis set used to describe the quantum system. This is then used to determine whether 3d orbitals can energetically and geometrically overlap with fluorine's 2p to participate in bonding in hypervalent compounds.
Computer Science
Presented by: Matthew Abbay, Matthew Guerrero, Ray Tran, Andy Ninh, Cody Wolfe. RummyBuddy. Advised by: Professor Elaine Weltz and Dr. Aaron Dingler, Dept. of Computer Science. [abstract]RummyBuddy is a gin rummy game application built for Windows and MacOS by Diamond Dogs, a team of developers with a passion to learn about A.I. from the ground up. RummyBuddy features a uniquely futuristic user interface and houses an A.I. built based on the famous Monte Carlo method. RummyBuddy is being developed in Unity3D and Visual Studio (C#) environments.
Presented by: Rida Abidi, Destiny Cleary, Phuoc Doan and Katherine West. The RoB Survey. Advised by: Professor Elaine Weltz and Dr. Aaron Dingler, Dept. of Computer Science. [abstract]For our project, we have built a web application to host the RoB Survey for our clients Dr. Randy Franz and Dr. Don Lee from the School of Business, Government, and Economics. This web application allows users to take the survey and receive immediate, personalized feedback, and enables our clients to easily edit the automated survey.
Presented by: Hector Dominguez-Maceda, Alex Lopez, Marissa Mar and Vanessa Mastrosimone. SPU2YOU. Advised by: Dr. David Wicks, School of Education.
[abstract]Virtual Student is a web service that will allow students at Seattle Pacific University to use telepresence robots to virtually attend and participate in class.
Our goal is to make a traditional classroom experience accessible to all students, since university students can be absent from class due to conflicts that inhibit them from physically and socially being a part of the classroom. Using our system, students are able to register to checkout a robot, determine if the robot is available for use, and check out and check in the robot. The robot’s functionality will include video, audio, and movement. We leveraged existing software and hardware from OhmniLabs to build our solution.
Presented by: Katy Graham, Janai Macklin, Sierra Maple and Shelley Waltar. Falcon Gym Project. Advised by: Professor Elaine Weltz and Dr. Aaron Dingler, Dept. of Computer Science. [abstract]We have developed an application to improve the accessibility and benefits of the fitness centers scattered around campus. Using QR codes and a mobile device, students and faculty will be able to quickly scan gym equipment and learn the proper use through videos created by the health and human performance department. Bring up the app and get Falcon Fit!
Presented by: Nathan Jenkins, Ash Palanisamy, Hung Nguyen and Jianhao Cai. Tenda. Advised by: Professor Elaine Weltz and Dr. Aaron Dingler, Dept. of Computer Science. [abstract]Tenda is an android application designed to measure the attendance of user created events.
Presented by: Josh McMorris, Abbe Blank, Daniel Gray and Erkin George. Puzzled. Advised by: Professor Elaine Weltz and Dr. Aaron Dingler, Dept. of Computer Science. [abstract]Puzzle hunts are a common way for corporations and universities to enjoy an activity encouraging creativity, problem solving, and teamwork. While various organizations have created puzzle hunt systems of their own, there is a not a solution for hosting puzzle hunts without internal overhead. To make puzzle hunts more accessible and easier to host, our team created a puzzle hunt system to allow users to create their own puzzle hunt events and participate in them.
Presented by: Sion Park, Bomin Kim, Jason Park and Conner Forche. Letter Run. Advised by: Professor Elaine Weltz and Dr. Aaron Dingler, Dept. of Computer Science. [abstract]Our project is a 2D platform game developed using open source technology .In the game, player has to control a character to collect letters to complete a word. The goal of the game is to reach the end door as fast as possible by collecting all the letters for a given word. It is available online for download and can be played without internet.
Presented by: Cody Tang, Jonathan Leung, Allen Huang and HaoXiang Liu. Blast to the Past. Advised by: Dr. Aaron Dingler, Dept. of Computer Science. [abstract]Anti-Meta is creating a Top-Down, Indie, RPG, Video Game made with Unity and Visual Studios. This is a story driven game where player will face enemies, obstacles, and puzzles to complete the game.
Engineering
Presented by: Fahad Abulhasan, Ali Alansari, Samantha Beck, Calvin Hancock and Joe Wahbeh. Safe Lock. Advised by: Dr. Daniel Keene, Dept. of Engineering. [abstract]Modeling a deadbolt self-locking mechanism with an alarm system that could be controlled via remote. The alarm would sense separation between the doorframe and the door, while the locking mechanism would reposition the deadbolt between the locked and unlocked positions.
Presented by: Anas Alhamad, Arik Espineli, Jasmine Gill, Jeff Smith and Miranda Sweigert. Autonomous Gantry Extinguishing System (A.G.E.S). Advised by: Dr. Adam Arabian, Dept. of Engineering. [abstract]Current research shows undetected machine fires can spread quickly, even compromising building structures and endangering lives. A.G.E.S is designed for the industrial/machine shop environment and is an overhead X-Y gantry system that attaches to existing ceiling infrastructure. Sensor boxes will be attached to machinery, and these will detect and locate a fire. This will trigger the movement of the X-Y ceiling gantry system to move to the fire location and actuate a fire extinguisher.
Presented by: Matthew Benzar, Alex Ortega, JJ Afaga, Katie Costley and Zachary Brant. S.P.E.C. 1.0. Advised by: Dr. Daniel Keene, Dept. of Engineering. [abstract]A low cost, solar powered, thermo-electric, portable cooler designed for lesser developed areas to transport medicine, food, and vaccines.
Presented by: Elli Fisher, Rylan Knepler, Sam Agyei, Christian Alfonso and Aaron Shen. One Small Step. Advised by: Dr. Daniel Keene, Dept. of Engineering. [abstract]Our project is a square tile that, when stepped on, produces electricity. It is collected in a battery to be used to power other devices.
Presented by: Cody Frost, Blake Fuller, Brianna Christensen, Chawni Read and Justin Lavigueure. GlideX. Advised by: Dr. Daniel Keene, Dept. of Engineering. [abstract]A wheelchair with unlimited degrees of freedom in its movement.
Presented by: Trevor Kinman, Sridevi Kinduri, Tai Doan, Katy Beth Smith and Austin Pischer. BikeGuard. Advised by: Professor Don Peter, Dept. of Engineering. [abstract]BikeGuard is a device that securely attaches to your bike and notifies you when your bike (or your bike lock) is being tampered with. Features include push-notifications when tampering occurs, tracking your bike via GPS, and Bluetooth connectivity.
Presented by: Zahra Lawal, Blake Paffile, Shayne Carpenter, Cyrus Christianson and Ilya Kramarevsky. Electrically Assisted Fluid Pump. Advised by: Dr. Daniel Keene, Dept. of Engineering. [abstract]The electrically assisted fluid pump is designed to be a low cost easy-to-use pump that can be operated with or without electricity to move a wide variety of fluids and be as versatile as possible in everyday life, especially in developing countries.
Presented by: Carson Miller, Andrew Miller, Dave Reyes Cordova, Seraj Alshakhoori and Connor Choi. Electric Aircraft Power Converter. Advised by: Dr. Adam Arabian, Dept. of Engineering. [abstract]The aerospace industry is exploring rising idea of recapturing energy, which would otherwise go lost or wasted during flight. Team Wing-It is designing and building a 4-switch buck-boost bidirectional DC to DC power converter to both deploy power to the aircraft systems, and could also be used in recapturing energy from the control surfaces on aircraft. It will handle diverse input of 20V-35.5V at 25A and execute a constant current and voltage depending on the state of the controller.
Presented by: Kirsten Noble, Coby Olson, Cai Dunham, Jon Xayasy and Matt Ranney
. OASISS. Advised by: Dr. Adam Arabian, Dept. of Engineering.
[abstract]The OASISS is an optimized water condensing unit designed for deployment in emergency and disaster relief situations to provide clean water to communities around the world.
Presented by: Julian Preijers, Karl Mazur, Qusai AlTalib, Mishaal Alotaibi, Graham Murphy. Hydro-Electric Power Generator. Advised by: Dr. Daniel Keene and Professor Don Peter, Dept. of Engineering. [abstract]A portable and durable device that uses a river or stream to spin a turbine. The turbines rotation will generate power to be stored in a separate power bank to charge handheld devices.
Presented by: Robo-Medics (Lorena Ferreira, Leanna Temple, Joanna Dickinson, Nick Sharp and Erin Okuna). Pill Bot. Advised by: Dr. Adam Arabian, Dept. of Engineering. [abstract]An autonomous robot that is placed within medical facilities and navigates to specific rooms at designated times to deliver medication to nurses/patients.
Presented by: Keith Spitzer, Zach Anderson, Quinton Cline, Khaled Ahmed Khaled and Suliman Buzakouk. Extinguisher Pro. Advised by: Dr. Daniel Keene and Professor Don Peter, Dept. of Engineering. [abstract]Junior design Project. A fire suppression system which holds 2 fire extinguishers in a user worn backpack and routes the flow down a users arm for extinguishing fires and embers caused by industrial tasks that produce sparks or fire as a byproduct in volatile environments. Aimed at people of the OSHA job title “Fire Watch”. * Best Poster awardee
Presented by: Alex Tran, David Meyer, Kieran Jackson, Grant Kalfus and Linnea Weicht. Remote Item Manipulator. Advised by: Dr. Adam Arabian, Dept. of Engineering. [abstract]The Remote Item Manipulator (RIM) is a remotely controlled arm designed to work in the presence of corrosive chemicals, like hydrofluoric acid. The operator of this arm will send commands to the RIM to manipulate objects within the hazardous environment while remaining out of harm themselves.
Presented by: Vi Tran, Chris Anderson, Marshall Kabat and Jacob Gamboa. Muscle Guide. Advised by: Dr. Adam Arabian, Dept. of Engineering. [abstract]Electromyography device that sends muscle signal data via bluetooth to track muscle movement of athletes.
Presented by: Tyler Wadekamper, Jonathan Ho, John Kim, Joshua Mason and Luke Swatosh. VAST Automated Storage. Advised by: Dr. Adam Arabian, Dept. of Engineering. [abstract]VAST is a tall storage shelf that automatically stores heavy items for people who use a wheelchair. The unit stores items at a height of up to 7 feet, then retrieves them at the press of a button.
Mathematics
Presented by: Jezen Alexander, Jian Zhao and Christian Alfonso. Strategy for Countering Opioid Crisis.U Advised by: Dr. Wai Lau, Dept. of Mathematics. [abstract]sing mathematical models, our project examines America's opioid crisis by taking the data for five states, and draws conclusions regarding the sources of the opioids and the trend of drug usage over a five year period.
Presented by: Mark Brumberg, Linnea Weicht and Kole Yoshimura. How to Feed Your Dragon. Advised by: Dr. Wai Lau, Dept. of Mathematics. [abstract]We model possible living conditions and arrangements for three dragons, based on the dragons from Game of Thrones. We consider various factors such as the dragons’ growth, their dietary needs, the cost of keeping food for the dragons, the climate, and more.
Presented by: Rebecca Butler, Jessica Fossum, and Leslie Mavrakis. The Aftermath: Optimizing Medical Resource Allocation via Quadcopter Post-Disaster. Advised by: Dr. Wai Lau, Dept. of Mathematics. [abstract]Optimizing emergency response efforts, this project offers a possible plan for disaster relief. Specifically targeting Puerto Rico after Hurricane Maria, this plan uses drones to deliver resources to five key hospitals and also capture video surveillance of hardest hit areas. Cargo containers are strategically packed with chosen ratios of three different types of medical packages, and drone flight paths are designed to optimize storage and route distances to sustain hospitals for nearly two years. * Best Poster awardee
Presented by: Robert Chung, Ian Starkey and Tait Weicht. Getting a Move on When the Louvre's Bombed. Advised by: Dr. Wai Lau, Dept. of Mathematics. [abstract]The Louvre is a famous museum in Paris. In an event of an emergency, it is crucial to evacuate people while effectively allowing emergency personnel to get to a target location. In this paper, we model the Louvre as a network and analyze how evacuation occurs in different scenarios with multiple models. We identify bottlenecks, potential threats, and possible solutions – which we use to propose policies and make recommendations to the Louvre’s emergency management team. * Best Poster awardee
Presented by: Mary Kate La Bar, Destiny Cleary and Sarah Farrell. Game of Ecology: Modeling the Life of Dragons. Advised by: Dr. Wai Lau, Dept. of Mathematics. [abstract]In the fictional television series Game of Thrones, three dragons are raised by Daenerys Targaryen. We were tasked to model aspects of a dragon's life given this context. We have analyzed the ecological requirements and impacts that dragons would have on today’s world if they were to exist. Join us as we explore the magical land of dragons!
Physics
Presented by: Arik Espineli. Kinematics and Forces of Lead Climbing. Advised by: Dr. Lane Seeley, Dept. of Physics. [abstract]What goes up must come down. That is important to understand when rock climbing. As a climber moves up a wall, the amount of potential energy they have increases. When the climber falls a lot of their stored potential energy is about to be transformed into kinetic energy. This research looks into the kinematics and forces involved with falling rock climber through theoretical modeling, experimentation, and data analysis. * Best Poster awardee
Presented by: Jonathan Ringdahl. Sagnac Interferomter. Advised by: Dr. John Lindberg, Dept. of Physics. [abstract]An exploration of sagnac interferometers, and some applications for it.
Sociology
Presented by: Cailin Dahlin. Counternarratives in Hip Hop Music: Themes of Marginalization. Advised by: Dr. Kevin Neuhouser, Dept. of Sociology. [abstract]Despite its popularity, hip hop music faces harsh criticism, with some people claiming that it promotes violence, drugs and misogyny. Others laud hip hop for challenging social problems as well as representing marginalization and black experiences. To investigate the legitimacy of these contrasting discourses surrounding hip hop, I have examined the lyrical content of hip hop songs looking for common themes, using a sample of 150 popular hip hop songs from 2003-2017.