Karisa Pierce

Department of Chemistry
Seattle Pacific University
Seattle, WA 98119-1997
(206) 281-2102
piercek@spu.edu

Research Interests:Using gas chromatography-mass spectrometry, liquid chromatography with fluorescence and absorbance detection, and dynamic mobility spectrometry to answer questions about complex samples such as: What are the statistically significant chemical differences among fuels and fuel blends? What toxins are present in marine organisms? What are some new applications of differential mobility spectrometry?

Education 

2007 – Ph.D. Analytical Chemistry, University of Washington (UW), February 8, 2007
2002 – B.S. Chemistry, Seattle University (SU), degree certified by American Chemical Society (ACS)

Associate Professor Seattle Pacific University (2008 – present) Teaching: Analytical Chem (CHM 3225, 3227, 3228, 3229), General Chem (CHM 1211, 1212), Intro to Research Methods (CHM 2960), University Seminar (USEM 1000), Intro to Nature of Science (CHM 1110), Introductory Inorganic Chem (CHM 2540), Undergrad Research (CHM 4960). Research: Develop chemometrics for multidimensional chromatography, applications for differential mobility spectrometry, advise and mentor Undergraduate Research Assistants, identify and quantify paralytic shellfish toxins in marine organisms. Invited reviewer for textbook chapters written for nonmajors’ chemistry courses.

Visiting Assistant Professor Seattle University (W07 – Su08) General Chemistry and Quantitative Analysis.

Graduate Research Assistant University of Washington (F02 – W07) Advisor: Robert Synovec, Ph.D. Developed chemometric tools for chromatographic retention time alignment, feature selection, data mining, and pattern recognition for analysis of GC-FID, GC-MS, GC×GC, and GC×GC-TOFMS separations. UW Research Associate (2007)

Consulting (2007 – present): Chevron Energy Technology Co. (2009–2012), Amgen Inc (Su2007), Authentix Inc (2010), New Mexico State University with Prof. Gary Eiceman (2013 – 2016, National Science Foundation Grant No. CHE-1306388)

Publications (Undergraduate Research Assistants are underlined; a note indicates if work was invited or peer-edited, otherwise all works underwent the traditional anonymous peer-review; *corresponding author):

  1. D Pasupuleti, GA Eiceman, KM Pierce*. Talanta (2016) 155:278-288.
  2. DK Pinkerton, KM Pierce, RE Synovec. Series: Data Handling in Science and Technology. Volume 30: Resolving Spectral Mixtures. Chapter 10: Chemometric Resolution of Complex Higher Order Chromatographic Data with Spectral Detection, Ed. Cyril Ruckebusch, 2016, Elsevier, Oxford, ISBN-13:  978-0444636386. Peer-edited.
  3. Dedeepya Pasupuleti, KM Pierce, Gary Eiceman. Journal of Chromatography A. (2015) 1421: 162-170.
  4. ML Strawn, ET Lunsford, LE Larsen, MM Moran, V Allbritton, RP Ferrer, KM Pierce*. Journal of Environmental Analytical Chemistry (2015) Volume 2 Issue 4: 148-153. http://dx.doi.org/10.4172/jreac.1000148.
  5. KM Pierce, BA Parsons, RE Synovec. Series: Data Handling in Science and Technology. Volume 29: Fundamentals and Analytical Applications of Multi-way Calibration. Chapter 10: Pixel-level data analysis methods for comprehensive two- dimensional chromatography, Ed. AC Olivieri, 2015, Elsevier, Oxford,  ISBN-13:  9780-444635273. Peer-edited.
  6. RP Ferrer, ET Lunsford, C Candido, Madison L Strawn, KM Pierce. Integrative and Comparative Biology (2015) icv010v1  doi: 10.1093/icb/icv010.
  7. KM Pierce*, JC Hoggard.  Analytical Methods (2014) 6 (3): 645 – 653.
  8. KM Pierce, B Kehimkar, L Marney, JC Hoggard, RE Synovec.  Journal of Chromatography A (2012) 1255: 3–11.
  9. Ying Luo and KM Pierce. “Development towards Rapid and Efficient Screening for High Performance Hydrolysate Lots in a Recombinant Monoclonal Antibody Manufacturing Process”  Biotechnology Progress  (2012) 28: 1061–1068.
  10. Stephen P. Schale, Trang M. Le, KM Pierce*. Talanta (2012) 94: 320–327.
  11. KM Pierce, JS Nadeau, RE Synovec. Handbook of Separation Science: Gas Chromatography Chapter 17: Data Analysis Methods,  Ed. Colin F. Poole, 2012, Elsevier, Oxford, ISBN 9780123855404. Peer-edited.
  12. KM Pierce*, Rachel E. Mohler.  Separation & Purification Reviews (2012) 41, 2: 143–168.
  13. Ying Luo, KM Pierce. Galenics, Amgen Process and Product Development Journal, Vol 7, November 2012:  25–36.
  14. KM Pierce*, Stephen P. Schale, Trang M. Le, Joel C. Larson, J. Chemical Education (2011) 88: 806–810.
  15. KM Pierce*, Stephen P. Schale.  Talanta (2011) 83: 1254–1259.
  16. KM Pierce*, E Bramanti, M Onor, R Spiniello, A Kangas, KJ Skogerboe, RE Synovec. Talanta (2010) 80: 1445–1451.
  17. KM Pierce, Jamin Hoggard, Rachel Mohler, Robert E. Synovec Journal of Chromatography A (2008) 1184: 341–352.
  18. Eric Burnham, L Bender, G Eiceman, Karisa Pierce, S Prasad.  Journal of Wildlife Management (2008) 72: 792–797.
  19. S Prasad, Karisa Pierce, H Schmidt, JV Rao, R Güth, RE Synovec, GB Smith, GA Eiceman, The Analyst (2008) 6: 760–767.
  20. S Prasad, K Pierce, H Schmidt, J Rao, R Güth, S Bader, R Synovec, G Smith, G Eiceman. The Analyst (2007) 132: 1031–1039.
  21. Karisa M. Pierce, Bob W. Wright, and Robert E. Synovec. Journal of Chromatography A (2007)  1141: 106–116.
  22. Rachel Mohler, K. Dombek, J. Hoggard, Karisa M. Pierce, E. Young, Robert Synovec. The Analyst (2007) 132:  756–767.
  23. Karisa M. Pierce, JC Hoggard, J Hope, P Rainey, et al.  Analytical Chemistry 78 (2006) 14: 5068–5075.
  24. N Watson, M VanWingerden, KM Pierce, B. Wright, R. Synovec.  Journal of Chromatography A 1129 (2006) 1: 111–118.
  25. Karisa M. Pierce, Janiece L. Hope, Jamin C. Hoggard and Robert E. Synovec. Talanta  70 (2006) 4: 797–804.
  26. Karisa M. Pierce, Janiece Hope, Robert E. Synovec. Lab Plus International (November 2005) Invited, peer-edited.
  27. Karisa M. Pierce, Lianna F. Wood, Bob W. Wright, and Robert E. Synovec.  Analytical Chemistry 77 (2005) 23: 7735–7743.
  28. Karisa M. Pierce, J.L. Hope, K.J. Johnson, B.W. Wright, R.E. Synovec.  Journal of Chromatography A (2005) 1096: 101–110.

Awards:

Tenured in 2014

Publication #12 recognized as one of the “Top Cited Articles from 2008 – 2009” published by J. Chromatogr. A., June 2011 “Highly Cited Author Award 2007 – 2009” from Journal of Chromatography A, June 2010

Best poster – Eigenvector University April 24, 2006

Best poster – Center for Process Analytical Chemistry conference May 3, 2005 Boris Weinstein Fellow (02-03), University of Washington, for academic excellence Seattle University Undergraduate Award in Analytical Chemistry (2001)

SU Bannan Scholar (2001)

Washington Scholar 1998 – 2002, for academic excellence

SU Presidential Scholar 1998 – 2002, for academic excellence

Service to the Scientific Community and to SPU:

Mentor and Advise Undergraduate Research Assistants (2004 – current)

Invited reviewer for anonymously peer-reviewed research journals, approximately once a month (2006 – current) Faculty Advisor of SPU Chapter of Student Affiliates of the ACS (2009 – current)

Academic Advisor (2009 – current)

Annual Science Workshop Teacher (2000 – 2007), Expanding Your Horizons Conference at Seattle University POGIL workshop June 20-22, 2008 Linfield College, McMinnville, OR

Faculty Member of SPU’s Admissions, Advising, and Retention Committee (AARC) (F11 to S14), Replacement Chair S14 Chair of AARC Faculty Committee (F14-S16)

Ways of Knowing Committee Representative for Dept of Chemistry and Biochemistry, 2011 – 2012

Puget Sound Section ACS Booth Volunteer at Seattle Science Center’s Annual Science Festival 2012 and 2013 Co-Chair of 2013 Puget Sound Section ACS Undergraduate Research Symposium, Seattle, WA April 27, 2013 Search Committee Faculty Rep for SPU VP EMM S14

SPU Faculty Council Member (S14-S16)

Moderated Analytical Chemistry Session of the Technical Program at NORM 6/26/12

Lectures:

  1. ACS Northwest Regional Meeting (NORM), 6/26/2012, Boise, ID “Predicting feedstock…using chemometrics…”
  2. Spring Mentoring Tea, SPU, 05/23/2012 “Undergraduate Research and a Parable”
  3. SPU Chemistry, Biology, and Physics Senior Capstone Seminar, 4/16/12, Seattle, WA “Chemometrics”
  4. Day of Common Learning Break-out Session, 10/19/2011, Seattle, WA “...Science and Faith…”
  5. SPU Faculty Retreat Break-out Session, 9/12/2011, Camp Casey, WA “Energy and Fuels”
  6. SPU Invited Speaker, 1/18/2008, Seattle, WA “Analyzing Complex Samples Using…”
  7. Xavier University, 11/09/2007, Cincinnati, OH “Using Chemometrics to Analyze Chromatographic Data.”
  8. Amgen Inc, 9/13/2007, Longmont, CO  “Screening peptone lots using chemometrics and NMR.”
  9. Amgen Inc, 8/24/2007, Thousand Oaks, CA “Screening peptone lots using chemometrics and NMR.”
  10. New Mexico State Univ., 12/06/2006, Las Cruces, NM “Interpreting Complex Data from One-Dimensional and…”
  11. CPAC Meeting, 11/07/2006, Seattle, WA “…Advancements in High-Speed GC, Multi-dimensional GC, and Data Analysis.”
  12. Chevron Energy Technology Co, 11/01/2006, Richmond, CA, “Complex Data from Multidimensional Chromatography”
  13. Pacific Northwest National Laboratories, 9/06/06, Richland, WA, “Advances in Gas Chromatography and Chemometrics”
  14. ExxonMobil, 7/10/2006, Clinton, NJ, “Extracting Information from Chromatographic Separations of Complex Samples.”
  15. KM Pierce, JC Hoggard, JL Hope, PM Rainey, ANHoofnagle, RM Jack, BW Wright and RE Synovec, 54th ASMS Conference, 5/31/06, Seattle, WA, “A Fisher Ratio Algorithm for Third Order Separation Instrumentation Data to Identify…”
  16. CPAC Meeting, 5/09/06, Seattle, WA “Addressing the Needs of Process Analysis through Advancements in High-Speed…”
  17. CPAC Meeting, 11/08/2005, Seattle, WA, “Chemometrics for multidimensional chromatographic analysis.”
  18. Federation of Applied Chemistry and Spectroscopy Societies, 10/10/2005, Quebec City, Canada, “Chemometrics…”
  19. DOW Chemical Co., 6/07/2005, Live web broadcast worldwide from Seattle, WA, “Gas Chromatography:  Advances in….”
  20. deCODE Genetics, Inc, 5/31/2005, Bainbridge Island, WA, “Chemometric Analysis of Gas Chromatographic Data…”
  21. International Symposium on Capillary Chromatography and Electrophoresis, 5/24/2005, Las Vegas, NV, “Chemometric Analysis of GC and GC×GC Data using Retention Time Alignment, Feature Selection, and Principal Component Analysis.”
  22. CPAC Meeting, 5/03/2005, Seattle, WA, “Chemometrics for multidimensional chromatographic analysis.”
  23. CPAC Meeting, 11/09/2004, Seattle, WA, “Process GC with Chemometrics.”
  24. Pacific Northwest National Laboratory, 11/01/2004, Richland, WA, “Objective Classification of Gasoline Samples…”
  25. Univ. of Wash. Dept. of Chemistry, 2/23/2004, Seattle, WA, “Fluorescence Polarization to Determine Fetal Lung Maturity.”

≥ 34 Other Presentations (*Presentations delivered by Undergraduate Research Assistants are starred):

  • ACS Northwest Regional Meeting, Anchorage, AK. 6/26/16. Poster presentation by KM Pierce. Classification of biodiesel and petrodiesel blends using gas chromatography-differential mobility spectrometry and dual ion filtering.
  • *14th Annual Erickson Conference at SPU, 5/13/16. Poster presentation by Angie Pell. Quantification of copper and lead in moss from Puget Sound region parks using flame atomic absorption spectroscopy and the standard addition method.
  • 249th ACS National Meeting, Denver, CO. 3/24/15. Poster presentation by KM Pierce. “Identification and quantification of paralytic toxins in Puget Sound marine organisms.
  • 24th ISIMS Conference, July 2015. D. Pasupuleti, K.M. Pierce, G.A. Eiceman. “Gas Chromatography and High Speed GC with Tandem Differential Mobility Detectors for Selective Detection of Methyl Linolenate and Fatty Acid Alkyl Esters in Biodiesel.” in absentia
  • Pittcon 2015, New Orleans, LA. 3/8/15. Oral presentation by G.A. Eiceman; co-authors M.R. Menlyadiev, D. Pasupuleti, K.M. Pierce, “GC with Tandem Differential Mobility Spectrometry” in absentia
  • 249th National ACS Meeting, Denver, CO. 3/23/15. Undergraduate student representatives presented the poster for SPU Chapter of Student Affiliates of the ACS.
  • *Murdock College Science Research Conference. 11/15/14. Oral presentation by Madison Strawn (F14). Quantification of Paralytic Toxins in Puget Sound Marine Organisms.
  • *Murdock College Science Research Conference. 11/14/14. Camillo M. Candido, Karisa M. Pierce, Ryan P. Ferrer. Poster. “Saxitoxin and the ochre sea star: Molecule of keystone significance and a classic keystone species”
  • *SPU Summer Research Institute 2014. 8/21/14. Oral presentation, Paralytic Shellfish Toxins, by Madison Strawn (F14).
  • *SPU Summer Research Institute 2013. 8/16/13. Oral presentation on Paralytic Shellfish Toxin project by Victoria Albritton.
  • *245th National ACS Meeting, New Orleans, LA. 4/8/13. ACS SPU Chapter poster with 5 undergraduate representatives.
  • *MJ Murdock Charitable Trust Research Conference at Whitman University, 10/26/2012. Meredith Moran (F12)
  • *10th Annual Erickson Conference at SPU, 5/11/12.  Two posters for projects by Brittany Raab (‘12) and Trang M. Le (‘12)
  • *Puget Sound Reg. ACS Undergrad Research Symposium, Seattle University, 4/28/12. TM Le (‘12), B Raab (‘12)
  • *MJ Murdock Charitable Trust Research Conference at Seattle University, 11/11/11. Trang Le (’12) and Lauren Larsen (’12)
  • *Ninth Annual Erickson Conference, 5/13/11, SPU. Oral presentation by Research Assistant Stephen Schale (’11)
  • *Ninth Annual Erickson Conference, SPU, 5/13/11. Three posters by Brittany Raab (’12), Trang Le (’12), Stephen Schale (’11)
  • *241st National ACS Meeting, Anaheim, CA, 3/28/11. Two research posters by Trang M. Le, Stephen P. Schale, Brittany Raab. In addition, other undergraduate student representatives presented the SPU ACS Student Section poster.
  • *Murdock Symposium 11/13/10 Linfield College, McMinnville, OR. Two posters by TM Le (’12), SP Schale (’11), B Raab (’12).
  • *Eighth Annual Erickson Conference at SPU, 5/14/10. Separate projects and posters by Trang M. Le and Stephen P. Schale
  • *Puget Sound ACS at Central Washington University, Ellensburg, WA. 5/1/10. Research poster by Stephen P. Schale
  • *239th National ACS Meeting, San Francisco, CA. 4/22/10. ACS SPU Chapter poster with 4 undergraduate representatives.
  • *Murdock Symposium 10/31/09 at Gonzaga University, Spokane, WA. Research project poster by Stephen P. Schale
  • *7th Erickson Conference 5/8/09, Seattle, WA. SPU. Three posters by A Kangas (’09), KL King (’10), SP Schale (’11).
  • *Puget Sound ACS Undergraduate Research Conference at University of Puget Sound 5/2/09, Tacoma, WA. Stephen Schale
  • Eigenvector University 5/6/08, Seattle, WA, “Chemometric Analysis of Complex NMR Spectral Data.”
  • 23rd  Int. Conf. on Yeast Genetics and Molecular Biology 7/1-6/07 Melbourne, Australia. ET Young, RE Mohler, KM Dombek, EM Humston, JC Hoggard, KM Pierce, RE Synovec “Comparison of Wild Type and Mutant Yeast Metabolomes Using Comprehensive GC x GC-TOFMS Data,” Poster #13-35. in absentia
  • Dalian International Symposia and Exhibition on Chromatography (DISEC), which included the 4th International GC x GC Symposium, Dalian, China, 6/4/07. “Discovery-Based Metabolomics using GC x GC-TOFMS and Chemometrics,”
  • RE Synovec, ET Young, RE Mohler, KM Dombek, JC Hoggard, EM Humston, KM Pierce, Invited Keynote Lecture, in absentia. Eigenvector University 4/24/06, Seattle, WA, “Correcting Retention Time Shifts in Chromatography….”
  • PittCon 3/16/06, Orlando, FL, “Correcting Retention Time Shifts in Chromatography for Improved Data Analysis.” in absentia
  • International Symposium on Capillary Chromatography and Electrophoresis 5/24/05, Las Vegas, NV, “Tools for the Extraction of Useful Information from Metabolic Profiles: Techniques for Mining the GC x GC-TOFMS Data Cube.”
  • PittCon 2/28/05, Orlando, FL, “Principles of Comprehensive 2D Separations with Chemometric Data Analysis,” RE Synovec, JL Hope, AE Sinha, BJ Prazen, KM Pierce, JC Hoggard, RE Mohler (Keynote Lecture – 2D Separations Session) in absentia
  • CPAC Meeting 11/03, Seattle, WA, “Process Gas Chromatography and Chemometrics.”
  • CPAC Meeting 5/03, Seattle, WA, “Process Gas Chromatography and Chemometric Analysis.”
  • CPAC Meeting 11/02, Seattle, WA, “Online measurement of interfacial properties: Dynamic surface tension detection.” 

≥ 900 Literature Citations according to Google Scholar.          https://scholar.google.com